ACTC lab is specializing on the development, analytical validation and clinical evaluation of molecular assays for the detection, enumeration and molecular characterization of CTCs.

More specifically, our main research interests are on:

a) study of micrometastasis through the development of singleplex and multiplex quantitative real time RT-qPCR assays for the detection of CTCs,

b) development and clinical evaluation of DNA methylation assays in fresh tissues, paraffin-embedded breast carcinomas, in CTCs and in cell-free circulating DNA,

c) development and clinical evaluation of quantitative real time RT-qPCR assays for the detection of mature micro RNAs in fresh tissues, paraffin-embedded breast carcinomas and in cell-free circulating DNA,

d) development and clinical evaluation of highly sensitive assays for mutation analysis in CTCs and in cell-free circulating DNA,

e) development and clinical evaluation of multiplex assays for gene expression in CTCs based on the Luminex bead array system.